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Montague BT, Hyperkalaemia in patients in hospital. All rights reserved.

Morgan DB, Wingo CS.
Gross P, To prevent cardiac conduction disturbances, intravenous calcium is administered to patients with hyperkalemic electrocardiography changes. Hoorn EJ, Effects of pH on potassium: new explanations for old observations. Zietse R, Dhalla IA, Charytan D, Donnelly T, Buller GK. Pennington LR, Cases A, Evans KJ, Neurologic signs of hypokalemia include generalized weakness and decreased deep tendon reflexes.Repeat measurement of serum potassium can help identify pseudohyperkalemia, which is common and typically results from potassium moving out of cells during or after sample collection.ECG should be considered if the potassium level is greater than 6 mEq per L; if there are symptoms of hyperkalemia; if there is suspicion of rapid-onset hyperkalemia; or among patients with underlying kidney disease, heart disease, or cirrhosis who have a new case of hyperkalemia. Onyanga-Omara F, You're right, lithium carbonate does "end" in #"CO"_3#, but a more accurate way of putting it would be that it contains the carbonate anion, #"CO"_3^(2-)#.. The lower melting point of the mixture (400–420 °C, or 750–790 °F) compared with that of pure lithium chloride (610 °C, or 1,130 °F) permits lower-temperature operation of the electrolysis. Schambelan M, Kim GH, Treatment of acute hyperkalaemia in adults. Weisberg LS. Ward DE, Gennari FJ. Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: a population-based cohort study. Tonelli M, Walton T, Potassium disorders are common. Soar J, )Calcium chloride, 10 mL of 10% solution IV over 5 to 10 minutes, or calcium gluconate, 30 mL of 10% solution IV over 5 to 10 minutesStabilizes cardiac muscle cell membrane; no effect on serum potassium or total body potassiumMay potentiate digoxin toxicity; calcium chloride can cause phlebitis and tissue necrosisRegular insulin, 10 units IV followed immediately by 50 mL of 50% glucose (25 g) IVShifts potassium into cells; no effect on total body potassiumMay cause hypoglycemia; glucose is unnecessary if serum glucose level is > 250 mg per dL (13.9 mmol per L); additive effect when combined with albuterolShifts potassium into cells; no effect on total body potassiumCan cause tachycardia and thus should be used with caution in patients with underlying heart disease; potassium-lowering effect not reliable in all patients; additive effect when combined with insulinRectal: 30 to 50 g every 6 hours in a retention enemaBinds potassium in exchange for sodium; lowers total body potassiumAssociation with gastrointestinal complications, particularly when combined with sorbitol; should be avoided in patients at risk of abnormal bowel functionCalcium chloride, 10 mL of 10% solution IV over 5 to 10 minutes, or calcium gluconate, 30 mL of 10% solution IV over 5 to 10 minutesStabilizes cardiac muscle cell membrane; no effect on serum potassium or total body potassiumMay potentiate digoxin toxicity; calcium chloride can cause phlebitis and tissue necrosisRegular insulin, 10 units IV followed immediately by 50 mL of 50% glucose (25 g) IVShifts potassium into cells; no effect on total body potassiumMay cause hypoglycemia; glucose is unnecessary if serum glucose level is > 250 mg per dL (13.9 mmol per L); additive effect when combined with albuterolShifts potassium into cells; no effect on total body potassiumCan cause tachycardia and thus should be used with caution in patients with underlying heart disease; potassium-lowering effect not reliable in all patients; additive effect when combined with insulinRectal: 30 to 50 g every 6 hours in a retention enemaBinds potassium in exchange for sodium; lowers total body potassiumAssociation with gastrointestinal complications, particularly when combined with sorbitol; should be avoided in patients at risk of abnormal bowel functionPotassium can be removed via the GI tract or the kidneys, or directly from the blood with dialysis. What is the optimal serum potassium level in cardiovascular patients? Lillemoe KD, Hypokalemia and cardiovascular disease.

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