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Experts aren’t sure what causes autoimmune hepatitis.Doctors diagnose autoimmune hepatitis based on your medical history, a physical exam, blood tests, imaging tests, and liver biopsy. Joint pain 1); this picture is unusual for the various conditions listed previously.When interface hepatitis is absent or mild, AIH is unlikely, and care should be taken to prevent unnecessary therapy. It occurs when your immune system attacks your liver cells. In autoimmune hepatitis, a low‐magnification image strongly suggests the diagnosis because of prominent interface and zone 1 lobular hepatitis (Fig. A working model for its pathogenesis postulates that environmental triggers, a failure of immune tolerance mechanisms, and a genetic predisposition collaborate to induce a T cell–mediated immune attack upon liver Without treatment, autoimmune hepatitis may get worse and lead to complications, such as cirrhosis. Researchers have not found that eating, diet, and nutrition play a role in causing or preventing autoimmune hepatitis.The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and other components of the National Institutes of Health (NIH) conduct and support research into many diseases and conditions. Stomach pain This information comes from a database called the If you need medical advice, you can look for doctors or other healthcare professionals who have experience with this disease. High liver enzymes These medicines may cause side effects. all the symptoms listed. Autoimmune hepatitis (AIH) was the first liver disease for which an effective therapeutic intervention, corticosteroid treatment, was convincingly demonstrated in controlled clinical trials. These include: Graves disease This form of hepatitis is an autoimmune disease. Signs and symptoms in people with autoimmune hepatitis range from mild to severe depending on the amount of liver damage present. A doctor can use a liver biopsy to look for the features of autoimmune hepatitis and to check for cirrhosis.Doctors treat autoimmune hepatitis with medicines that suppress your immune system, most often corticosteroids—prednisone or prednisolone—with or without azathioprine. Joint inflammation Blotchy loss of skin color