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Never cut a skin patch. Selegiline wordt bij lichtere klachten soms gebruikt als medicijn om mee te beginnen. Selegiline, also known as L-deprenyl and sold under the brand names Eldepryl and Emsam among others, is a medication which is used in the treatment of Parkinson's disease and major depressive disorder.
https://www.webmd.com/drugs/2/drug-95200/selegiline-transdermal/details However, you should continue to use transdermal selegiline even if you feel well. In de latere gecompliceerde fasen met responsfluctuaties (zoals ‘on-off’ en 'wearing-off') tijdens de levodopa-behandeling zijn dopamine-agonisten (pramipexol, ropinirol), MAO-B-remmers (rasagiline, safinamide, selegiline) en COMT-remmers (entacapon) effectief als adjuvante behandeling. Follow these directions carefully. Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. Het Farmacotherapeutisch Kompas gebruikt analytische cookies om het gebruik van de website te analyseren en daarmee de website te kunnen verbeteren. It works by increasing the amounts of certain natural substances that are needed to maintain mental balance. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Be sure to keep all appointments for office visits with your doctor.The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with transdermal selegiline. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Do not apply selegiline patches to skin that is hairy, oily, irritated, broken, scarred, or calloused.After you apply a selegiline patch, you should wear it all the time until you are ready to remove it and put on a fresh patch. After you apply a selegiline patch, you should wear it all the time until you are ready to remove it and put on a fresh patch. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased.
Na staken van fluoxetine minimaal vijf weken wachten, voor met selegiline te starten.Niet gelijktijdig gebruiken met sympathicomimetica, centraal dempende stoffen en alcohol.Bij gelijktijdig gebruik met dopamine de aanbevolen startdosis van dopamine terugbrengen tot 10%.Gecombineerd gebruik met orale anticonceptiva vermijden, omdat een sterk verhoogde biologische beschikbaarheid van selegiline is waargenomen en gegevens voor eventuele dosisaanpassing ontbreken.Vanwege de hoge eiwitbinding extra aandacht schenken bij combinatie met geneesmiddelen met een nauwe therapeutische breedte, zoals digoxine en anticoagulantia.Bij gelijktijdig gebruik van een MAO-A-remmer tyraminerijk voedsel als kaas en gistproducten vermijden.Veel contra-indicaties worden voorzichtigheidshalve vermeld vanwege de theoretisch niet uit te sluiten sympathicomimetische werking.Vanwege het mogelijke optreden van duizeligheid tijdens behandeling niet rijden en geen machines bedienen.Wees voorzichtig bij algemene anesthesie; er zijn meldingen van respiratoire en cardiovasculaire depressie, hypotensie en coma.Bij gebruik van een hogere dosering selegiline (> 30 mg/dag) is er een groter risico van een hypertensie na inname van tyraminerijk voedsel.Dit middel kan invloed hebben op de rijvaardigheid en het vermogen om machines te bedienen. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Niet 's avonds innemen.Als monotherapie: Vaak (1-10%): stijging van leverenzymwaarden, slaperigheid, slapeloosheid, verwarring, hallucinaties, dyskinesie, vertigo, hoofdpijn, duizeligheid, bradycardie, misselijkheid.Soms (0,1-1%): stemmingsverandering, supraventriculaire tachycardie, droge mond.Zelden (0,01-0,1%): onrust, aritmie, orthostatische hypotensie, huidreacties, hyperhidrose, mictiestoornissen.Verder is gemeld: hyperseksualiteit, urineretentie.Selegiline kan de bijwerkingen van levodopa versterken, zoals dyskinesie, misselijkheid, verwardheid, hallucinaties, hoofdpijn, orthostatische hypotensie, aritmieën en vertigo; de dosering van levodopa kan worden teruggebracht tot circa 30%, waarna deze bijwerkingen gewoonlijk verdwijnen.Gelijktijdig gebruik met MAO-remmers, antidepressiva (SSRI's, SNRI's, tricyclische antidepressiva), sympathicomimetica en opioïden (pethidine) is gecontra-indiceerd, vanwege mogelijk optreden van het serotoninesyndroom.
Information is also available online at Do not let anyone else take your medication. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not stop using transdermal selegiline without talking to your doctor.Apply selegiline patches to dry, smooth skin anywhere on your upper chest, your back (between your neck and your waist), your upper thigh, or the outer surface of your upper arm.
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