Weight gain from antibiotics is a clinical reality. Female mice fed olanzapine ate more and moved less, leading to excessive weight gain and other indications of metabolic syndrome similar to that seen in humans.
Earth & The Environment
Genetics & Genomics Cancer Since other existing anti-obesity and anti-diabetic medications have limited effectiveness against AATP-induced metabolic syndrome, this work offers hope that HTR2C activators like lorcaserin may be useful tools to prevent these side effects.
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Close more info about Why Do Antipsychotics Cause Weight Gain?
Mice who were fed olanzapine but also lacked the HTR2C protein did not overeat, develop altered glucose metabolism or insulin levels, or gain weight, indicating that HTR2C is important for these side effects. Videos Nearly all types of antipsychotic medications—such as olanzapine, clozapine, and risperidone—cause weight gain, according to 2017 research published in … Genetics & Genomics Immunology The work, performed by researchers at the University of Texas Southwestern Medical Center, was "Atypical antipsychotics are essential medications for millions of schizophrenia patients worldwide and they are increasingly being prescribed for bipolar disorder, major depressive disorder, and autism," commented Dr. Chen Liu, an Assistant Professor of Internal Medicine and Neuroscience. Close more info about Why Do Antipsychotics Cause Weight Gain? Obesity and diabetes often develop shortly after treatment begins." Cell & Molecular Biology
Cell & Molecular Biology
... To test this hypothesis, researchers fed mice the drug to reproduce the olanzapine blood concentrations seen during human olanzapine therapy. Drug Discovery & Development
Youâll probably gain more if youâre taking an antipsychotic for the first time.Talk to your doctor about potential weight gain before you start an antipsychotic.