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Arch Dermatol 140(9):1065-9 (2004 Sep). Epub 2014 Sep 17.Indian J Dermatol.
Segmental vitiligo has also been difficult to repigment. Topical tacrolimus and the 308nm excimer laser: a synergistic combination for treatment of vitiligo. A review of clinical features, Fitzpatrick skin type and response to topical tacrolimus were recorded. Silverberg NB, Lin P, Travis L, Farley-Li J, Mancini AJ, Wagner AM, Chamlin SL, Paller AS.J Am Acad Dermatol. Patients with vitiligo were treated with tacrolimus 0.03% for children ages 2-15 years of age and tacrolimus 0.1% ointment for individuals 16 years of age or older, applied twice-daily to all hypopigmented or depigmented lesions. Unable to load your delegates due to an error 2014 Nov;8(5):1433-1437. doi: 10.3892/etm.2014.1975.
Our results demonstrate that the combination treatment of 0.1% tacrolimus ointment plus 308-nm MEL and 308-nm MEL monotherapy are effective, safe, and well tolerated for the treatment of vitiligo compared to treatment with vitamin E. Furthermore, this study suggests that an association with topical … J Eur Acad Dermatol Venereol 21(7):916-20 (2007 Aug). Repigmentation in active vitiligo was superior to that in stable vitiligo.
2007 Jan-Feb;17(1):55-61. doi: 10.1684/ejd.2007.0093. We found 29 studies from 2002 to 2014.
Online ahead of print.An Bras Dermatol.
Wiley Online Library.
Of these, 83.3% patients showed some repigmentation at theIn 2008, Choi et al.2 studied 79 patients; 52 were treated with tacrolimus and 27 with topical corticosteroids.
80% of patients with segmental vitiligo of the head and neck showed some response to tacrolimus, but there was no statistical significance between segmental and vulgaris vitiligo. Passeron T, Ostovari N, Zakaria W, et al. D Fai, N Cassano, GA Vena, Narrow‐band UVB phototherapy combined with tacrolimus ointment in vitiligo: a review of 110 patients, Journal of the European Academy of Dermatology and Venereology, 10.1111/j.1468-3083.2006.02101.x, 21, 7, (916-920), (2007).
2006 Sep 21;126(18):2370-2.Lee JH, Kwon HS, Jung HM, Lee H, Kim GM, Yim HW, Bae JM.JAMA Dermatol. Unable to load your collection due to an error Lan C, Wu C, Chen G, et al. Please enable it to take advantage of the complete set of features! Epub 2007 Feb 27.Tidsskr Nor Laegeforen. Vitiligo, an acquired pigmentary skin disorder affecting 1% of the world’s population, is characterized by depigmented macules that correspond histologically withImmunomodulators, such as tacrolimus ointment 0.1% and 0.03% (Protopic®, Astellas), and pimecrolimus cream 1% (Elidel®, Novartis) are approved for treatingTacrolimus acts on T cells and mast cells, inhibiting T cell activation and the production of proinflammatory cytokines, such as Tumor Necrosis Factor (TNF),Xu et al.1 studied 30 vitiligo patients who were treated with tacrolimus ointment for 4 months or more. Narrow-band UVB phototherapy combined with tacrolimus ointment in vitiligo: review of 110 patients. Wiley Pooling the lesions, 50% repigmentation of vitiligo patches was never achieved before 2 months of treatment, with a peak after 6 months of therapy. Topical immunomodulators were found to be asIn a placebo-controlled 12-month prospective study of 31 vitiligo patients, Hartmann et al.4 documented the safety and efficacy of tacrolimus, even in those withMany studies suggest the associated use of tacrolimus with other therapeutic options to improve the rate of repigmentation.8-10 Lotti et al.8 studied 458 patients withThe association of tacrolimus with NBUVB excimer laser has been reported to improve the repigmentation rate, but it is associated with the possibility ofSilverberg et al.12 reported that the use of tacrolimus ointment is an effective alternative treatment for vitiligo in children, particularly involving head and neckTacrolimus ointment is effective and safe for treating vitiligo, especially when it is located on the head and neck, or when the disease is long-lasting. 2016 Apr;91(2):187-95. doi: 10.1590/abd1806-4841.20164012.Garcia-Melendez ME, Salinas-Santander M, Sanchez-Dominguez C, Gonzalez-Cardenas H, Cerda-Flores RM, Ocampo-Candiani J, Ortiz-López R.Exp Ther Med. doi: 10.1111/j.1365-4632.2009.03852.x.
Methods: A total of 88 patients with vitiligo were enrolled in this study. This site needs JavaScript to work properly.
2010 Feb;37(2):125-9. doi: 10.1111/j.1346-8138.2009.00774.x.Passeron T, Ostovari N, Zakaria W, Fontas E, Larrouy JC, Lacour JP, Ortonne JP.Arch Dermatol.
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