";s:4:"text";s:4275:" Department of Medicine, Innlandet Hospital Trust Division Lillehammer, Lillehammer, Norway
daily dose 5 mg if eGFR 30–60 mL/minute/1.73 m 2; max. Follow
The Assessment of Treatment with Lisinopril and Survival (ATLAS) trial reported significantly better outcomes in patients treated with high doses of lisinopril when compared with low-dose users.As with any non-randomized, observational design, the present study may be subject to unmeasured confounders.
The relevant plot is shown in Cox regression analyses for all-cause mortality regarding angiotensin-converting enzyme inhibitor use in the predefined subgroups for the propensity score-matched cohorts. Search for other works by this author on:
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For the purpose of the present analysis, patients were censored as ‘alive’ at the date of this last contact. Patients were eligible for the study if they met Medication was at the discretion of the referring physician. enalapril, ramipril, lisinopril and Corresponding author.
Asterisk in Cox regression analyses for all-cause mortality regarding angiotensin-converting enzyme inhibitor use in the predefined subgroups for the propensity score-matched cohorts. 0000026182 00000 n
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enalapril), the closest match of a patient receiving a different ACEI (e.g. All-cause mortality was the predefined endpoint of the study.In order to prevent bias in further statistical analyses due to missing baseline values, we performed a multiple imputation analysis with Differences in event-free survival between patients treated with enalapril, lisinopril, or ramipril were analysed using Cox proportional hazard models and displayed using the Kaplan–Meier method for survival. Compared with enalapril and benazepril, captopril has a greater propensity for GI adverse effects and a shorter half-life in dogs, necessitating more frequent dosing; thus, its use has fallen out of favor. 0000025004 00000 n
Department of Cardiology, Oslo University Hospital, Ulleval and Institute of Clinical Sciences, University of Oslo, Oslo, Norway
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Then, the first step of the matching process was repeated to identify the next closest match to the given enalapril patient of the failed match according to the propensity score. 73 37
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