";s:4:"text";s:6707:" Unfortunately, Seroquel has many unwanted side effects that can present even in people who take the substance as directed. The condition does not have any cure, but with appropriate medical treatment and psychological support, bipolar disorder symptoms can be controlled. Symptoms of bipolar disorder include mood changes and manic and depressive episodes. Visit the MedicineNet does not provide medical advice, diagnosis or treatment. We're available 24/7 to answer questions and help you make decisions about starting recovery from drug use. Look for the medically reviewed badge ( If you feel that any of our content is inaccurate or out-of-date, please let us know at Seroquel is the brand name for an atypical, second generation antipsychotic drug called quetiapine.1 As a prescription medication used to treat serious mental illnesses like bipolar disorder and schizophrenia, qutiapine is a valuable pharmaceutical tool used by practitioners to mitigate certain mental health symptoms and improve the wellbeing of their patients.2″Despite the many benefits of Seroquel (quetiapine), the drug carries a risk of side effects and some danger of lasting health consequences. Worried about your substance use? Seroquel side effects might go away as a person gets used to having the drug in their system or be so serious that this specific medication cannot be tolerated. The adverse reactions leading to discontinuation in 2% or more of patients on Seroquel and at a greater incidence than placebo were somnolence (4.1% vs. 1.1%) and In therapy for schizophrenia (up to 6 weeks), the most commonly observed adverse reactions associated with the use of quetiapine in adolescents (incidence of 5% or greater and quetiapine incidence at least twice that for placebo) were somnolence (34%), dizziness (12%), dry mouth (7%), tachycardia (7%).In bipolar mania therapy (up to 3 weeks) the most commonly observed adverse reactions associated with the use of quetiapine in children and adolescents (incidence of 5% or greater and quetiapine incidence at least twice that for placebo) wereIn an acute (8-week) Seroquel XR trial in children and adolescents (10-17 years of age) with bipolar depression, in which efficacy was not established, the most commonly observed adverse reactions associated with the use of Seroquel XR (incidence of 5% or greater and at least twice that for placebo) wereThe following findings were based on a 6-week placebo-controlled trial in which quetiapine was administered in either doses of 400 or 800 mg/day.Table 13 enumerates the incidence, rounded to the nearest percent, of adverse reactions that occurred during therapy (up to 6 weeks) of schizophrenia in 2% or more of patients treated with Seroquel (doses of 400 or 800 mg/day) where the incidence in patients treated with Seroquel was at least twice the incidence in placebo-treated patients.Adverse reactions that were potentially dose-related with higher frequency in the 800 mg group compared to the 400 mg group includedThe following findings were based on a 3-week placebo-controlled trial in which quetiapine was administered in either doses of 400 or 600 mg/day.In bipolar mania therapy (up to 3 weeks) the most commonly observed adverse reactions associated with the use of quetiapine in children and adolescents (incidence of 5% or greater and quetiapine incidence at least twice that for placebo) wereTable 14 enumerates the incidence, rounded to the nearest percent, of adverse reactions that occurred during therapy (up to 3 weeks) of bipolar mania in 2% or more of patients treated with Seroquel (doses of 400 or 600 mg/day) where the incidence in patients treated with Seroquel was greater than the incidence in placebo-treated patients.Adverse reactions that were potentially dose-related with higher frequency in the 600 mg group compared to the 400 mg group includedIn a short-term placebo-controlled monotherapy trial in adolescent patients with schizophrenia (6-week duration), the aggregated incidence of extrapyramidal symptoms was 12.9% (19/147) for Seroquel and 5.3% (4/75) for placebo, though the incidence of the individual adverse reactions (akathisia, tremor, extrapyramidal disorder, hypokinesia, restlessness, psychomotor hyperactivity, muscle rigidity, dyskinesia) did not exceed 4.1% in any treatment group.In a short-term placebo-controlled monotherapy trial in children and adolescent patients with bipolar mania (3-week duration), the aggregated incidence of extrapyramidal symptoms was 3.6% (7/193) or Seroquel and 1.1% (1/90) for placebo.Table 15 presents a listing of patients with adverse reactions potentially associated with extrapyramidal symptoms in the short-term placebo-controlled monotherapy trial in adolescent patients with schizophrenia (6-week duration).Table 16 presents a listing of patients with adverse reactions associated with extrapyramidal symptoms in a short-term placebo-controlled monotherapy trial in children and adolescent patients with bipolar mania (3-week duration).In placebo-controlled monotherapy clinical trials involving 3368 patients on quetiapine fumarate and 1515 on placebo, the incidence of at least one occurrence of neutrophil count <1.0 x 10In the acute (6-week) schizophrenia trial in adolescents, increases in heart rate (>110 bpm) occurred in 5.2% (3/73) of patients receiving Seroquel 400 mg and 8.5% (5/74) of patients receiving Seroquel 800 mg compared to 0% (0/75) of patients receiving placebo. Our Cytoxan (cyclophosphamide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Learn simple...False ideas scare many depression suffers away from therapy and the quick relief and help these pros can provide. Young people who suffer from depression or another mental illness and who abuse Seroquel recreationally may be hesitant to disclose their symptoms to a doctor for fear of getting in trouble and may not get the proper treatment.Many prescription and illicit drugs are associated with certain withdrawal symptoms when use is stopped or drastically reduced after the body has become accustomed to the substance’s presence in the body.These Seroquel withdrawal effects are uncomfortable, but they are a normal and expected part of the process. Quetiapine (Seroquel) is an atypical antipsychotic that is mainly used in the treatment of schizophrenia and bipolar disorder.