";s:4:"text";s:3663:" Letrozole, however, which may tell the median of hormonal forms of action tumors that need estrogen to treat in the use. The likelihood of drug interactions increases as the number of drugs being taken increases. Identify these significant letrozole oral (Femara Oral) drug interactions with the RxList drug interaction checker tool. No dosage modification is recommended for patients with mild to moderate hepatic impairment, however, therapy with letrozole should be administered cautiously to patients with severe hepatic impairment. CTC grade 3-4 hypercholesterolemia was reported in 0.4% of letrozole patients and 0.1% of tamoxifen patients. The following side effects have been reported by at least 1% of people taking this medication. The interaction may increase or decrease the effectiveness of the drugs or the side effects of the drugs. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.These medications may interact and cause very harmful effects. Early-stage, hormone receptor–positive (HR+) breast cancer in women who have already received other treatment. If you miss a dose, take it as soon as possible and continue with your regular schedule. Interactions. Letrozole has no known severe interactions with other drugs. Does Letrozole Interact with other Medications? Letrozole belongs to the group of cancer-fighting medications known as Letrozole can be used after surgery to treat postmenopausal women with Letrozole fights breast cancer by inactivating an enzyme known as Each yellow, round shaped, shallow concave, film coated tablet, having 6 mm diameter debossed with "N" on one side and "L" on the other side, contains 2.5 mg of letrozole. Femara is an anti-estrogen estrogen drug used for oral use women with cirrhosis no. Letrozole is extensively metabolized by the liver. down the sink or in the toilet) or in household garbage. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. No dosage modification is recommended for patients with mild to moderate hepatic impairment, however, therapy with letrozole should be administered cautiously to patients with severe hepatic impairment.Moderate Potential Hazard, Moderate plausibility. Also in the adjuvant setting, an increase of >=1.5 X ULN in total cholesterol (generally non-fasting) was observed in patients on monotherapy who had baseline total serum cholesterol within the normal range (i.e., <=1.5 X ULN) in 151/1843 (8.2%) on letrozole vs 57/1840 (3.2%). Consideration should be given to monitoring serum cholesterol.Moderate Potential Hazard, Moderate plausibility. These medications are not usually taken together. Identify these serious letrozole oral (Femara Oral) drug interactions with the RxList drug interaction checker tool.