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MC or low‐dose MC, can be defined as the oral administration of chemotherapy at relatively low, minimally toxic doses, on a frequent or continuous schedule of treatment, with no extended drug‐free breaks. However, this decision must be made by your veterinarian, as they know your dog best.Never, ever change the dose of prednisone without checking with your vet first, because your dog can suffer a Either it will be filled in your veterinarian’s office, or you’ll take a prescription to a pharmacy to get the medication filled (most human pharmacies can fill canine prescriptions, especially for common drugs like prednisone).The most common form of prednisone you’ll receive is a pill—a white tablet. We don’t call it a “miracle” for nothing.
So, for those individuals, prednisolone is the preferred drug.However, for dogs who are healthy—or who have a health condition that doesn’t affect their liver—either form of the drug may be used.For the sake of simplicity, I’ll use the term ‘prednisone’ throughout this article—but the same information generally applies to prednisolone, too.Also, prednisone is commonly shortened to ‘pred’ in conversation—so I’ll use that term in this article, too.Besides prednisone and prednisolone, commonly used glucocorticoids in pets include hydrocortisone, dexamethasone, methylprednisolone, triamcinolone, and others.These drugs are steroids. We cannot examine your dog and/or give you veterinary advice. And truly, prednisone does greatly improve the quality of life for many dogs.That being said, no medication is perfect. Some owners swear that giving fiber rich foods like pumpkin puree clears up their doggy’s stomach really well! Dulcolax is the brand name of the stimulant laxative called Bisacodyl which is sold as an over the counter medicine in the form of oral tablets, suppositories and enemas. It’s also helpful in treating sudden allergic reactions, such as a swollen muzzle following a bee sting.Along the same lines, prednisone can also be very helpful for ear infections.The ear canals are an extension of the skin, and therefore ear problems often benefit from similar treatments to skin problems.Prednisone is helpful with a wide variety of cancers, especially lymphoma.Sometimes, prednisone is used as part of a chemotherapy protocol and has a direct effect on cancer growth and spread.Other times, it’s used for what we call “palliative therapy,” meaning that whether or not it changes the course of the disease, it can make your dog feel a lot better.While it’s not right for every dog nor every type of cancer, for some patients, prednisone can really give them a good quality of life. Without it, your vet can’t be sure you are maximizing the positive effects of pred while minimizing the risk of negative side effects.That way, any changes to blood values will be easier to interpret.Note that prednisone itself can cause some increases in liver function values. It thereby minimizes side effects. We have found that these changes are usually NOT indicative of a problem in the actual functioning of the liver.But these changes in liver values CAN make some tests confusing to interpret. Do not skip a dose of chemo. It can also make the diagnosis of lymphoma (and thus the planning for treatment) more difficult.With that rule in mind, here are the most common ways prednisone is used to treat lymphoma…The protocol you choose depends on many factors, such as your dog’s specific type and stage of lymphoma, any other health problems, and many other factors including your finances and your own personal beliefs or preferences.
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