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Please be aware that as additional data is submitted to ECHA, the brief profile will also be updated to reflect the new situation. If so, the data provided is not processed for the Brief Profile.This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.This section displays the values related to endocrine disrupter mammalian screening from all registered dossiers for the substance.If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. Suspendisse porttitor leo quis purus porttitor posuere sit amet sit amet nunc.
1 000 g will be displayed as 1 kg.Due to the number of the substances and the associated information, substance data is processed and aggregated in an automatic process. Otherwise data is displayed as provided by the registrant(s).The availability of additional data beyond the five results displayed is indicated by (…).Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. Danazol Lithium Diethyl stilbesterol Misoprostol Phenytoin NSAIDS Oral hypoglycaemic agents [Tetracycline’s Isotretinoin, etretinate Thalidomide Valproic acid Trimethadone Warfarin Psycho active drugs CNS and limb malformations[2] Prolonged renal failure in neonate, renal tubular dysgenesis, decreased skull ossification 2] Neonatal meconium ileus If so, the data provided is not processed for the Brief Profile.This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.This section summarises the values related to toxicity to soil macroorganisms (except arthropods) from all registered dossiers for the substance.
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. The percentage is based on the count of values provided.For substance’s physical state at 20°C and 1 013 hPa, registrants can classify their substance as:For substance’s form, registrants can classify their substance as:For substance’s odour, registrants can classify their substance as: For substance’s type, registrants can classify their substance as:Summary data is collected from the endpoint summary(ies) provided by registrants of REACH dossiers.For substance’s physical state at 20°C and 1013 hPa, registrants can classify their substance as:This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications.This section summarises the melting and freezing point values from all registered dossiers for the substance.More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’.If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).Results without measurement conditions (pressure) are not processed for the Brief Profile. If more than one result with the same value, data is further prioritised by test type and endpoint conclusion.Data is generally displayed in milligrams per kilogram bodyweight per day.This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.This section displays the values related to genetic toxicity from all registered dossiers for the substance.For this endpoint registrants do not provide study results that are processable for the Brief Profile.Processable data for study results is prioritised by endpoint conclusion: the most conservative value is displayed.This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.This section displays the values related to carcinogenicity from all registered dossiers for the substance.Study results are not processed for carcinogenicity in the context of Brief Profiles due to the use of complex field(s) to report the information, which cannot be easily summarised by an automatic algorithm.Processable data for summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor.
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. For other data an order of magnitude logic might apply; e.g.
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