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Therefore, it should be used with caution in patients receiving such agents. Drugs inhibiting peristalsis are contraindicated in this situation.Caution should be used when prescribing Clindamycin to individuals with a history of gastro-intestinal disease, especially colitis.Periodic liver and kidney function tests should be carried out during prolonged therapy.
Date of first authorisation/renewal of the authorisationStart typing to retrieve search suggestions. The use of clindamycin may result in overgrowth of non-susceptible organisms, particularly yeasts. Each blister contains 8 capsules.100's: Polypropylene container with low density polyethylene tamper evident lids.Any unused medicinal product or waste material should be disposed of in accordance with local requirements Park View, Riverside Way, Watchmoor Park, Camberley, Surrey, GU15 3YL, UKTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. Fatalities have been reported.Reporting suspected adverse reactions after authorisation of the medicinal product is important. This may be fatal.The appearance of marked diarrhoea should be regarded as an indication that the product should be discontinued immediately. Neonates (0-28 days), especially if premature, require special attention to dose reductions and/or extended dose intervals due to the prolonged elimination half-life.Clindamycin capsules are not suitable for children who are unable to swallow them whole. Most Gram-negative aerobic bacteria, including the Enterobacteriaceae, are resistant to clindamycin. The possibility of sensitivity should be borne in mind.Orally and parenterally administered clindamycin has been reported to appear in human breast milk in ranges from 0.7 to 3.8μg/mL. The presence of the disease may be further confirmed by culture of the stool for It is important to consider the diagnosis of CDAD in patients who present with diarrhoea subsequent to the administration of antibacterial agents. If possible, mothers should stop breast-feeding during therapy. Therefore, Clindamycin should only be administered to pregnant women if the potential benefit is considered to outweigh the possible risk to the foetus.After multiple doses, amniotic fluid concentrations were approximately 30% of maternal blood concentrations.In clinical trials with pregnant women, the systemic administration of clindamycin during the second and third trimesters has not been associated with an increased frequency of congenital abnormalities. It diffuses across the placenta into the fetal circulation and appears in breast milk. Insert the amount of one applicator, which is around 100 mg of clindamycin, into the vagina once daily at bedtime for 3 or 7 consecutive nights.To use a suppository, insert one suppository pill, which is equivalent to 100 mg of clindamycin, into the vagina once daily at bedtime for three consecutive nights.People with a history of colitis should not use clindamycin creams or suppositories.A person with acne can apply a thin layer of Cleocin T 1% lotion or clindamycin 1% solution to the affected area of skin twice a day.A person can apply Clindagel 1% once daily to the affected area when acne appears.If a person has a very serious infection and they cannot take other antibiotics, they may receive injectable clindamycin in the hospital.One of the most common side effects of a majority of antibiotics is diarrhea. If allowed to progress, it may produce peritonitis, shock and toxic megacolon. Dosage in Renal /Hepatic Impairment: Clindamycin dosage modification is not necessary in patients with renal or hepatic insufficiency.Note: In cases of beta-haemolytic streptococcal infection, treatment with Clindamycin should continue for at least 10 days to prevent subsequent rheumatic fever or glomerulonephritis.Oral. If an allergic reaction occurs therapy should be with the usual emergency treatments, including corticosteroids, adrenaline and antihistamines.Pharmacotherapeutic group: Antibacterials for Systemic Use. The BSAC-recommended breakpoints for staphylococci are S: ≤ 0.5 μg/ml; R: ≥ 1.0 μg/mlThe following table lists organisms according to their inherent susceptibility to clindamycin.
Give oral fluids for severe vomiting and diarrhoea if required.
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