";s:4:"text";s:4988:" The chemical name of methocarbamol is 3‑(2‑methoxyphenoxy)‑1,2-propanediol 1‑carbamate and has the empirical formula of CMethocarbamol is a white powder, sparingly soluble in water and chloroform, soluble in alcohol (only with heating) and propylene glycol, and insoluble in benzene and The mechanism of action of methocarbamol in humans has not been established, but may be due to general CNS depression.
Robaxin (methocarbamol injection, USP) Injectable, a carbamate derivative of guaifenesin, is a central nervous system (CNS) depressant with sedative and musculoskeletal relaxant properties.
Supportive measures include maintenance of an adequate airway, monitoring urinary output and vital signs, and administration of intravenous fluids if necessary. Hypersensitivity; Renal impairment (parenteral) Effects of Drug Abuse Robaxin has a relatively short half-life. Do not take Robaxin if you are allergic to methocarbamol or any ingredients contained in this drug. You may need to reduce your dose after the first 2 or 3 days of treatment. This caution is necessary because of the presence of polyethylene glycol 300 in the vehicle.A much larger amount of polyethylene glycol 300 than is present in recommended doses of Robaxin Injectable is known to have increased pre-existing acidosis and urea retention in patients with renal impairment. Methocarbamol is a central nervous system depressant that is used to treat involuntary muscle spasms. Patients should be cautioned about operating machinery, including automobiles, until they are reasonably certain that methocarbamol therapy does not adversely affect their ability to engage in such activities.As with other agents administered either intravenously or intramuscularly, careful supervision of dose and rate of injection should be observed. Call your doctor for medical advice about side effects. The mean (± SD) elimination half-life in the cirrhotic patients and the normal subjects was 3.38 (± 1.62) hours and 1.11 (± 0.27) hours respectively. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. It is a sterile, pyrogen-free solution intended for intramuscular or intravenous administration.Each mL contains: methocarbamol, USP 100 mg, polyethylene glycol 300, NF 0.5 mL, Water for Injection, USP q.s. Keep the bottle tightly closed when not in use.Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. It does not, however, replace the usual procedure of debridement, tetanus antitoxin, penicillin, tracheotomy, attention to fluid balance, and supportive care. Available for Android and iOS devices. Although the amount present in this preparation is well within the limits of safety, caution dictates this contraindication.Robaxin Injectable is contraindicated in patients hypersensitive to methocarbamol or to any of the injection components.Since methocarbamol may possess a general CNS depressant effect, patients receiving Robaxin Injectable should be cautioned about combined effects with alcohol and other CNS depressants.Safe use of Robaxin Injectable has not been established with regard to possible adverse effects upon fetal development. This medicine is only part of a complete treatment program that may also include rest, physical therapy, or other pain relief measures.Robaxin oral is taken by mouth. Select one or more newsletters to continue.