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Khattak FH, Morris IM, Branford WA "Simvastatin-associated dermatomyositis."
Although not all of these side effects may occur, if they do occur they may need medical attention. Ann Pharmacother 40 (2006): 1880-351. Gregoor PJ "Atorvastatin may cause nightmares." Krasovec M, Elsner P, Burg G "Generalized eczematous skin rash possibly due to HMG-CoA reductase inhibitors." Side Effects.
Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
There have been rare postmarketing reports of hepatic failure.1. McDonagh J, Winocour P, Walker DJ "Musculoskeletal manifestations during simvastatin therapy." Curr Opin Lipidol 16 (2005): 640-723. Ann Intern Med 137 (2002): I457. 2002
Lancet 341 (1993): 11457. Study Casts Doubt on Value of Cholesterol Drugs
Spironolactone tablets, 25 mg contain the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, docusate sodium 85%/sodium benzoate 15%, entrapped peppermint flavor, magnesium stearate, microcrystalline cellulose, povidone, and sodium starch …
Mukhtar RY, Reckless JP "Statin-induced myositis: a commonly encountered or rare side effect?" Ann Pharmacother 36 (2002): 820-337. "Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs." Nephron 89 (2001): 117-835. van Puijenbroek EP, Du Buf-Vereijken PW, Spooren PF, van Doormaal JJ "Possible increased risk of rhabdomyolysis during concomitant use of simvastatin and gemfibrozil." Diaczok BJ, Shali R "Statins unmasking a mitochondrial myopathy: a case report and proposed mechanism of disease." Lancet 344 (1994): 1383-952.
Diseases & Conditions Sundram F, Roberts P, Kennedy B, Pavord S "Thrombotic thrombocytopenic purpura associated with statin treatment." Adverse Drug Reactions Advisory Committee (ADRAC) and the Adverse Drug Reactions Unit of the TGA "Australian Adverse Drug Reactions Bulletin. We comply with the HONcode standard for trustworthy health information - Alvarez JM, Rawdanowiz TJ, Goldstein J "Rhadbdomyolysis after coronary artery bypass grafting in a patient receiving simvastatin." J Neurol Neurosurg Psychiatry 58 (1995): 625-844. The incidence of myopathy with the 80 mg dose has been reported as disproportionately higher than that observed at lower doses and the risk of myopathy with simvastatin 80 mg/day is greater compared with other Persistent elevations in transaminases of up to 3 times the upper limit of normal (3xULN) have been reported in 1% of patients. J Intern Med 240 (1996): 403-436. Am J Med 117 (2004): 823-949.
Ann Pharmacother 30 (1996): 1922. Ann Pharmacother 36 (2002): 288-9521. JAMA 275 (1996): 55-60Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some side effects may not be reported. Gynecomastia in men, hirsuitism in women ---.Eplerenone Hyperkalemia. Raynaud's disease causes pain in the extremities in response to cold temperatures or stress.
Gonyeau MJ "Statins and osteoporosis: a clinical review."
http://www.medscape.com/resource/lipid-metabolic
With therapy discontinuation or interruption, transaminase levels generally returned to pretreatment levels.
Pharmacotherapy 26 (2006): 1190-250. Finsterer J, Zuntner G "Rhabdomyolysis from Simvastatin triggered by infection and muscle exertion." Kidney Int 56 (1999): s117-214. Grundy SM "Can statins cause chronic low-grade myopathy?" O 018.
Halkin A, Lossos IS, Mevorach D "HMG-CoA reductase inhibitor-induced impotence." This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Muldoon MF, Ryan CM, Sereika SM, Flory JD, Manuck SB "Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adults."
/viewarticle/910856 J Am Geriatr Soc 54 (2006): 70-645.
2001 Contact the applicable plan
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If you log out, you will be required to enter your username and password the next time you visit. Itakura H, Vaughn D, Haller DG, O'Dwyer PJ "Rhabdomyolysis from cytochrome p-450 interaction of ketoconazole and simvastatin in prostate cancer." Br J Rheumatol 33 (1994): 1998. Pharmacotherapy 26 (2006): 414-2242. Am J Med 108 (2000): 351-210. Nakad A, Bataille L, Hamoir V, Sempoux C, Horsmans Y "Atorvastatin-induced acute hepatitis with absence of cross-toxicity with simvastatin." Pharmacotherapy 25 (2005): 228-4327.
Morales K, Wittink M, Datto C, et al. Please confirm that you would like to log out of Medscape. Dermatology 186 (1993): 248-5253.
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