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If you would like more information, talk to your healthcare provider. Skin reactions consistent with hypersensitivity have been observed with organic nitrates.Venous and arterial dilatation as a consequence of nitroglycerin treatment including RECTIV, can decrease venous blood returning to the heart and reduce arterial vascular resistance and systolic pressure.
Do not use RECTIV for a condition for which it is not prescribed. Ergotamine is known to precipitate angina pectoris. Apply 1 inch of ointment (375 mg of ointment equivalent to 1.5 mg of nitroglycerin) intra-anally every 12 hours for up to 3 weeks. What should I tell my healthcare provider before using RECTIV?Tell your healthcare provider about all your medical conditions, including if you:Tell your healthcare provider about all the medicines you takeWe comply with the HONcode standard for trustworthy health information -
Exercise caution when treating patients with any of the following conditions: blood volume depletion, existing hypotension, cardiomyopathies, congestive heart failure, acute myocardial infarction, or poor cardiac function for other reasons. RECTIV (nitroglycerin) Ointment 0.4% is available in tubes with a one-inch dosing line on the carton allowing the measurement of approximately 375 mg of nitroglycerin ointment 0.4% (1.5 mg nitroglycerin) for application.Nitroglycerin forms free radical nitric oxide (NO), which activates guanylate cyclase, resulting in an increase of guanosine 3',5'-monophosphate (cyclic GMP) in smooth muscle and other tissues.
Increased sensitivity may reflect the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.Nitroglycerin toxicity is generally mild. Clinical data from the published literature indicate that the elderly demonstrate increased sensitivity to nitrates, which may be therapeutic but also manifest by more frequent or severe hypotension and related dizziness or fainting. RECTIV may lower your blood pressure. https://www.webmd.com/drugs/2/drug-159329/rectiv-rectal/details If you have a headache, you may take over-the-counter painkillers (such as acetaminophen), or ask your doctor whether you should stop taking RECTIV.Dizziness, faintness on standing, or light-headednessThis website uses cookies and other technologies to personalize content and to show you more personalized ads (for example, Google Ads and Facebook) on this and other websites, as well as provide you with social media features
Pain as assessed by the change in VAS from baseline to Days 14-18 was lower in patients receiving 0.4% ointment compared to placebo.
Frequently Asked Questions (FAQs) on RECTIV: Rectal ointment.
By clicking "Accept" you understand that you are directing Allergan to disclose your personal information, including internet tracking data (like cookies and the IP address you used to access this website), to these third parties for the purposes stated above. To obtain a 1.5 mg dose of nitroglycerin, the covered finger is laid alongside the 1 inch dosing line on the carton.The tube is gently squeezed until a line of ointment the length of the measuring line is expressed onto the covered finger. RECTIV (nitroglycerin) Ointment 0.4% is a prescription medicine used to treat moderate to severe pain caused by chronic anal fissures.
The effect may be more frequent in patients who have also consumed alcohol, since alcohol use contributes to hypotension. Marked orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used concomitantly.Beta-blockers blunt the reflex tachycardia produced by nitroglycerin without preventing its hypotensive effects.
An anal fissure is a tear in the skin lining the anal canal.RECTIV is not suitable for children and adolescents under the age of 18 years because it has not been assessed in people in this age group.RECTIV may lower your blood pressure. Links to other websites are provided as a service to you.
A finger covering, such as plastic-wrap, disposable surgical glove or a finger cot, should be placed on the finger to apply the ointment.
Carefully smear the ointment around the inner sides of the anal canal.
You may report side effects to FDA at 1-800-FDA-1088.The product information provided in this site is intended only for residents of the United States.
Rectogesic 4 mg/g Rectal Ointment is indicated in adults for relief of pain associated with chronic anal fissure.
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