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Your Name: (optional) Labs were staged at 3c. I guess you’re really on your own but most of us sadly don’t have all the info we need. It is not a substitute for professional medical advice. Megace (megestrol): “I was diagnosed with endometrial cancer (very early stage) at age 40. ; Weiner, Louis M., M.D. Phase II clinical study of 17.

It makes sense, but I think my old doctor was who I needed when I needed him and I am grateful for his "old school" practices for my particular circumstances. They can also cause muscle and joint aches. Female sex steroid receptors in postmenopausal endometrial carcinoma and biochemical response to antiestrogen. 20 In addition, the efficacy of progestin in the … If taken for a long time (years), these drugs can weaken bones, sometimes leading to osteoporosis. Who would comprehensively know that? January 19, 2018. The way I understand it the tamoxifen enhances the estrogen receptors and hells the Megace work  Therefore, you couldn’t stop the Megace and just take tamoxifen but I might be wrong  My oncologist said it in reverse. Even after the ovaries are removed (or are not working), estrogen is still made in fat tissue. Surgeon said it looked like endometriosis had exploded in there. Temsirolimus with or without megestrol acetate and tamoxifen for endometrial cancer: a gynecologic oncology group study. If taken for a long time (years), these drugs can weaken bones, sometimes leading to osteoporosis. Clipboard, Search History, and several other advanced features are temporarily unavailable. I had surgery in july 2015. Wolters Kluwer Health Glad to know the Megace clotting issue is rare but because I already had a stroke....I’m on Eliquis already so I hope that’s enough. His daughter is a pathologist and his absolute pride and joy, so when I was resistant to having radiation therapy, she was invovled in the back and forth about it when Megace instead of radiation was an option being discussed. It’s not the same as the hormone therapy given to ease the symptoms of menopause (Hormone treatment for endometrial cancer When I am on megace I feel as though I am starving.

Cancer Chemother Rep 1966; 50: 163–70.11. It was Moekay's post about origin, myometrial invasion, and lymphovascular invasion that eventually helped me to go along with the recommendation for radiation and compared to that I had no problem taking Megace, too.My new gyn-onc at Dana Farber says that taking Megace for prevention is an old school practice and discontinued it last September when I moved to MA and switched to him for follow-up care.

This article has been saved into your User Account, in the Favorites area, under the new folder endometrial thickness dropped from approximately 2 cm to a few mm in 6 months. I did have minor side effects like dry skin and constipation so I'm on a lower dose. Accessed at www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq/ on February 13, 2019.American Cancer Society medical information is copyrighted material. It doesn't cause bone loss, but it can cause hot flashes and vaginal dryness. Women taking tamoxifen also are at higher risk for serious blood clots in the legs.Most women with endometrial cancer have had their ovaries removed as a part of treatment.

Jerzak KJ, Duska L, MacKay HJ. Eligible patients also had to have Eastern Cooperative Oncology Group performance status of 0, 1, or 2 as well as adequate bone marrow, renal, and hepatic functions, unless abnormalities were caused by metastatic disease. Megace made me extremely hungry and I put on weight and then when I was on the tamoxifen I had the worst bone pain specifically in my left leg where there were no mets. can include:At this time, no one type of hormone treatment has been found to be the best for endometrial cancer.

They've been found to be useful in treating women with endometrial cancer who want to be able to get pregnant in the future, and this is an area of research interest. I got a new PCP when he quit her practice.I was started on Megace as a preventative measure about a month after I finished RT by my original gyn-onc who was treating me like I was his daughter with my diagnosis..i.e.

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